The San Francisco 49ers (3-0) take a three-game winning streak into a meeting against the Arizona Cardinals (1-2) on Sunday, October 1, 2023 at Levi's Stadium, and we have best bets recommendations.

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When is 49ers vs. Cardinals?

  • Game Date: Sunday, October 1, 2023
  • Time: 4:25 PM ET
  • TV: FOX
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Watch the NFL live all season long with Fubo!

Best Moneyline Bet

  • The spread for this matchup suggested by the model (13 points) is slightly less than the 15-point edge BetMGM gives to the 49ers, though the data still has them as the favorite.
  • Based on this contest's moneyline, the 49ers' implied win probability is 91.7%.
  • The 49ers have not yet lost a game they played as the moneyline favorite this season, going 3-0.
  • San Francisco has yet to play a game with moneyline odds of -1100 or shorter.
  • This season, the Cardinals have won one out of the three games in which they've been the underdog.
  • Arizona has not entered a game this season with longer moneyline odds than +700.

Who will win? The 49ers or Cardinals? Head to BetMGM and make your pick!

Against the Spread Pick

  • Pick ATS: Arizona (+15)
  • The 49ers have covered the spread two times this season (2-1-0).
  • The Cardinals are 3-0-0 against the spread this year.

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Best Over/Under Pick

  • Pick OU: Over (44)
  • Between them, these two teams average 10 more points per game (54) than this matchup's over/under (44).
  • Opponents of the two teams average a combined 7.7 fewer points per game (36.3) than this matchup's over/under of 44 points.
  • One of the 49ers' three games with a set total has hit the over (33.3%).
  • Two of the Cardinals' three games with a set total have hit the over (66.7%).

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