Tuesday's contest at Oracle Park has the San Francisco Giants (74-70) matching up with the Cleveland Guardians (68-77) at 9:45 PM ET (on September 12). Our computer prediction projects a close 7-6 victory for the Giants, so it should be a tight matchup.

The Giants will look to Sean Manaea (5-5) against the Guardians and Cal Quantrill (2-6).

Giants vs. Guardians Game Info & Odds

  • When: Tuesday, September 12, 2023 at 9:45 PM ET
  • Where: Oracle Park in San Francisco, California
  • How to Watch on TV: MLB Network
  • Live Stream: Watch this game on Fubo!

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Giants vs. Guardians Score Prediction

Our pick for this contest is Giants 7, Guardians 6.

Total Prediction for Giants vs. Guardians

  • Total Prediction: Over 8.5 runs

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Explore More About This Game

Giants Performance Insights

  • In four games as the favorite over the last 10 matchups, the Giants have a perfect record of 4-0.
  • In its last 10 games with a total, San Francisco and its opponents have failed to hit the over four times.
  • Sportsbooks have not set a spread for any of the Giants' last 10 games.
  • The Giants have entered the game as favorites 70 times this season and won 38, or 54.3%, of those games.
  • San Francisco has a record of 10-4 in games when sportsbooks favor them by at least -185 on the moneyline.
  • Oddsmakers have implied with the moneyline set for this matchup that the Giants have a 64.9% chance to win.
  • San Francisco has scored 623 runs (4.3 per game) this season, which ranks 21st in MLB.
  • The Giants have a 4.05 team ERA that ranks 11th among all MLB pitching staffs.

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Giants Schedule

Date Opponent Score Pitching Matchup
September 6 @ Cubs L 8-2 Alex Wood vs Jordan Wicks
September 8 Rockies W 9-8 Kyle Harrison vs Ty Blach
September 9 Rockies W 9-1 Logan Webb vs Chase Anderson
September 10 Rockies W 6-3 Keaton Winn vs Peter Lambert
September 11 Guardians W 5-4 Alex Cobb vs Gavin Williams
September 12 Guardians - Sean Manaea vs Cal Quantrill
September 13 Guardians - Kyle Harrison vs Logan Allen
September 14 @ Rockies - Alex Cobb vs Chase Anderson
September 15 @ Rockies - Logan Webb vs Peter Lambert
September 16 @ Rockies - Alex Cobb vs Kyle Freeland
September 17 @ Rockies - TBA vs Chris Flexen