Coco Crisp, Jed Lowrie and Seth Smith homered to back up a solid performance by starter Bartolo Colon in his return from a drug suspension, and the Oakland Athletics beat the Houston Astros 6-3 on Saturday night.
It was the first appearance for Colon (1-0) since he received a 50-game suspension for a positive testosterone test Aug. 22. He allowed eight hits and three runs without a walk in six innings for the win.
Crisp homered for the second straight game with a solo shot in the fourth that put Oakland up 1-0.
Lowrie, who spent last season with the Astros, added a solo homer in Oakland's four-run sixth inning. Derek Norris gave the A's the lead with a run-scoring single later in the sixth.