Cubs starter Carlos Zambrano left Sunday's game against the Florida Marlins with a left hamstring strain.
Zambrano led off the fifth inning with a bunt single, but appeared to hurt himself while stretching to beat the throw from Marlins pitcher Ricky Nolasco.
Pitcher Rich Harden pinch-ran for Zambrano, then scored four batters later on Derrek Lee's grand slam to give Chicago a 6-2 lead.
Zambrano allowed two runs on four hits in five innings, striking out three and walking one. Angel Guzman relieved Zambrano in the sixth.
Copyright 2013 Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.