Manu Ginobili is out for the rest of the season and the playoffs.
The Spurs guard underwent scans on Monday that showed his troubled right ankle has gotten worse. Ginobili missed 19 games after the All-Star break before coming back late last month.
The Spurs said tests showed Ginobili had an increased narrow edema and stress fracture in his right distal fibula.
Ginobili did not play in the fourth quarter in Sunday's loss at Cleveland.
The news is a huge blow to the Spurs with the postseason just a few weeks away. San Antonio plays at Oklahoma City on Tuesday.