May 21, 2013

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Reporter: Associated Press Email

FDA Approves New Targeted Breast Cancer Drug

WASHINGTON (AP) - The Food and Drug Administration says it has approved a new form of a best-selling breast cancer drug that targets tumor cells while sparing healthy ones.

The drug Kadcyla (kad-SY'-luh) from Roche combines the established drug Herceptin with a powerful chemotherapy and a third chemical linking the medicines together. The chemical keeps the drugs intact until they bind to a cancer cell, where the double-shot of medication is released.

The FDA approved the drug for about 20 percent of breast cancer patients who have a particular form of the disease. These patients have tumors that overproduce the protein HER-2.

The approval will help Roche build on the success of Herceptin, which has long dominated the breast cancer marketplace. The drug had sales of $6 billion last year.


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