Interstate 5 in San Diego was back open Friday afternoon after a sheriff's bomb squad destroyed a device found along the roadway that forced closure for several hours.
Police were not immediately able to provide more details on the device.
The California Highway Patrol in San Diego closed the highway in both directions after reports of a pipe bomb on the southbound side of the freeway.
Officer Larry Landeros said the freeway and several off-ramps were closed at around 12:30 p.m. between State Route 52 and the Interstate 805 junction in northern San Diego.
Interstate 5 is the main north-south artery between Los Angeles and the U.S.-Mexico border.