Crews began working to demolish the 84-year-old Mizpah Hotel Thursday after it was deemed "dangerous," Information Officer Steve Frady said.
Frady said beams in the Mizpah's basement were beginning to split.
"Much of the temporary shoring that was put in so we can conduct safe operations for investigators and search and recovery of the victims is now taking the weight of the building, there is a fear that the building will in fact collapse," Frady said.
Processing of the crime scene is finished and no additional victims are believed inside the structure, Frady said. Twelve people are believed to have been killed in the fire at the hotel.
Frady said a portion of the building, constructed in 1925, may remain standing. The fate of businesses that share the same building as the Mizpah is not known. One business-owner said he cleared everything he could out of his business there.