Joe Martin has been a trucker on the road for more than 20 years.
He says driving on holidays is always dangerous.
"If you're going to spend any time on the road, being tired is a part of driving. But, there's no substitute for rest and when a person does recognize they're becoming tired, you become not as alert. And, you can become a danger to other people around you."
Most truckers will tell you a good night sleep is the best preparation for a long day's drive.
Since 26-thousand Nevadans are expected to drive more than fifty miles from home this weekend, Sgt. Pat Dreelan with the Reno Police Department says you will be sharing the road with others.
"The best thing you can do is plan ahead and just know your trip is going to be time consuming. There's a lot of people on the roadways, a lot of traffic. A lot of people who are tired and worn out over the weekend. So, the best thing you can do is get some sleep, plan your routes, know your limitations."
Joanne Gerow and her husband decided to skip the holiday traffic altogether and spend the last day relaxing at home.
"We left early. We went to Winnemuca for the Winnemuca Run and came back a day ahead of time because we didn't want to be in the traffic."
Plan stops or just use the scenic viewpoints or rest stops to stretch your legs and get a fresh breath before heading on.
Drowsiness can sink in quickly, and Sgt. Dreelan says it can be responsible for a deadly crash.
"A lot of things are happening. You're required to scan ahead, look for obstacles in the road. If you're drowsy, it just impairs your ability to be alert and react to something that's right in front of you or spot something in the road."
Martin reminds everyone that it only takes one person and one bad mistake.
"It only takes a second to have a tradition on the highway."